CA3

GENE INFORMATION

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Gene name

CA3 (HGNC Symbol)

Synonyms

CAIII, Car3

Description

Carbonic anhydrase III, muscle specific (HGNC Symbol)

Entrez gene summary

Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10.3 kb and contains seven exons and six introns. [provided by RefSeq, Oct 2008]

Chromosome

8

Cytoband

q21.2

Chromosome location (bp)

85373436 - 85449040

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000164879 (version 78.38)

Entrez gene

761

UniProt

P07451 (UniProt - Evidence at protein level)

neXtProt

NX_P07451

Antibodypedia

CA3 antibodies
 

PROTEIN VIEW

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CA3-001
 
CA3-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CA3-001 ENSP00000285381
ENST00000285381
P07451
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Show » Show » 260 29.6 No 0
CA3-005 ENSP00000429760
ENST00000520921
E5RHI4
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Show » 19 2.2 No 0