SPINK1

GENE INFORMATION

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Gene name

SPINK1 (HGNC Symbol)

Synonyms

PCTT, PSTI, Spink3, TATI

Description

Serine peptidase inhibitor, Kazal type 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis. [provided by RefSeq, Oct 2008]

Chromosome

5

Cytoband

q32

Chromosome location (bp)

147824568 - 147831786

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000164266 (version 78.38)

Entrez gene

6690

UniProt

P00995 (UniProt - Evidence at protein level)

neXtProt

NX_P00995

Antibodypedia

SPINK1 antibodies
 

PROTEIN VIEW

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SPINK1-001
 
SPINK1-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SPINK1-001 ENSP00000296695
ENST00000296695
P00995
Show all »
Show » Show » 79 8.5 Yes 0
SPINK1-002 ENSP00000427376
ENST00000510027
D6RIU5
Show all »
Show » Show » 65 7 Yes 0