PRSS12

GENE INFORMATION

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Gene name

PRSS12 (HGNC Symbol)

Synonyms

BSSP-3, MRT1

Description

Protease, serine, 12 (neurotrypsin, motopsin) (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the trypsin family of serine proteases. Studies in mouse suggest that the encoded enzyme may be involved in structural reorganizations associated with learning and memory. The enzyme is also expressed in Leydig cells in the testis, but its function in this tissue is unknown. Defects in this gene are a cause of mental retardation autosomal recessive type 1 (MRT1). [provided by RefSeq, Jul 2010]

Chromosome

4

Cytoband

q26

Chromosome location (bp)

118280038 - 118353003

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000164099 (version 78.38)

Entrez gene

8492

UniProt

P56730 (UniProt - Evidence at transcript level)

neXtProt

NX_P56730

Antibodypedia

PRSS12 antibodies
 

PROTEIN VIEW

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PRSS12-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PRSS12-001 ENSP00000296498
ENST00000296498
P56730
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