SUCLG1

GENE INFORMATION

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Gene name

SUCLG1

Synonyms

Description

Succinate-CoA ligase, alpha subunit (HGNC Symbol)

Entrez gene summary

This gene encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP. Mutations in this gene are the cause of the metabolic disorder fatal infantile lactic acidosis and mitochondrial DNA depletion. [provided by RefSeq, Feb 2010]

Chromosome

2

Cytoband

p11.2

Chromosome location (bp)

84423523 - 84460045

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000163541 (version 78.38)

Entrez gene

8802

UniProt

P53597 (UniProt - Evidence at protein level)

neXtProt

NX_P53597

Antibodypedia

SUCLG1 antibodies
 

PROTEIN VIEW

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SUCLG1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SUCLG1-001 ENSP00000377446
ENST00000393868
P53597
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