STK36

GENE INFORMATION

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Gene name

STK36 (HGNC Symbol)

Synonyms

FU, KIAA1278

Description

Serine/threonine kinase 36 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the serine/threonine kinase family of enzymes. This family member is similar to a Drosophila protein that plays a key role in the Hedgehog signaling pathway. This human protein is a positive regulator of the GLI zinc-finger transcription factors. Knockout studies of the homologous mouse gene suggest that defects in this human gene may lead to congenital hydrocephalus, possibly due to a functional defect in motile cilia. Because Hedgehog signaling is frequently activated in certain kinds of gastrointestinal cancers, it has been suggested that this gene is a target for the treatment of these cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]

Chromosome

2

Cytoband

q35

Chromosome location (bp)

218672026 - 218702716

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000163482 (version 78.38)

Entrez gene

27148

UniProt

Q9NRP7 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NRP7

Antibodypedia

STK36 antibodies
 

PROTEIN VIEW

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STK36-001
 
STK36-002
 
STK36-003
 
STK36-006
 
STK36-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

STK36-001 ENSP00000295709
ENST00000295709
Q9NRP7
Show all »
Show » Show » 1315 144 No 2
STK36-002 ENSP00000375954
ENST00000392105
Q9NRP7
Show all »
Show » Show » 1294 141.7 No 1
STK36-003 ENSP00000394095
ENST00000440309
Q9NRP7
Show all »
Show » Show » 1315 144 No 2
STK36-006 ENSP00000400055
ENST00000455724
C9J1B8
Show all »
Show » Show » 75 8.7 No 0
STK36-009 ENSP00000403527
ENST00000424080
C9JDA4
Show all »
Show » Show » 279 31.6 No 0