S100A12

GENE INFORMATION

? »

Gene name

S100A12 (HGNC Symbol)

Synonyms

CAAF1, CAGC, CGRP, ENRAGE, MRP6, p6

Description

S100 calcium binding protein A12 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity. [provided by RefSeq, Nov 2014]

Chromosome

1

Cytoband

q21.3

Chromosome location (bp)

153373706 - 153375649

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000163221 (version 78.38)

Entrez gene

6283

UniProt

P80511 (UniProt - Evidence at protein level)

neXtProt

NX_P80511

Antibodypedia

S100A12 antibodies
 

PROTEIN VIEW

? »
 
 
 
S100A12-001
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

S100A12-001 ENSP00000357726
ENST00000368737
P80511
Show all »
Show » Show » 92 10.6 No 0