PPAP2B

GENE INFORMATION

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Gene name

PPAP2B (HGNC Symbol)

Synonyms

LPP3, PAP-2b

Description

Phosphatidic acid phosphatase type 2B (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is a membrane glycoprotein localized at the cell plasma membrane. It has been shown to actively hydrolyze extracellular lysophosphatidic acid and short-chain phosphatidic acid. The expression of this gene is found to be enhanced by epidermal growth factor in Hela cells. [provided by RefSeq, Mar 2010]

Chromosome

1

Cytoband

p32.2

Chromosome location (bp)

56494747 - 56645301

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000162407 (version 78.38)

Entrez gene

8613

UniProt

O14495 (UniProt - Evidence at protein level)

neXtProt

NX_O14495

Antibodypedia

PPAP2B antibodies
 

PROTEIN VIEW

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PPAP2B-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PPAP2B-001 ENSP00000360296
ENST00000371250
O14495
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