SPC24

GENERAL INFORMATION

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Gene name

SPC24

Gene description

SPC24, NDC80 kinetochore complex component

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

6
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (bone marrow)
GTEx:Mixed

Protein evidence

Evidence at protein level

Protein localization

Gastro-intestinal tract, squamous epithelia, cells in seminiferous ducts, lymphoid tissues and hematopoeitic cells showed weak to moderate nuclear and occasional cytoplasmic positivity. Strong cytoplasmic staining was observed in a subset of Leydig cells and adrenal glandular cells. Cardiac and skeletal myocytes showed moderate staining. Remaining normal tissues were negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA051234
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (bone marrow)

Organ

Expression

GTEx dataset
RNA tissue category:  Mixed

Organ

Expression



GENE INFORMATION

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Gene name

SPC24 (HGNC Symbol)

Synonyms

FLJ90806, SPBC24

Description

SPC24, NDC80 kinetochore complex component (HGNC Symbol)

Entrez gene summary

Chromosome

19

Cytoband

p13.2

Chromosome location (bp)

11131520 - 11155808

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000161888 (version 78.38)

Entrez gene

147841

UniProt

Q8NBT2 (UniProt - Evidence at protein level)

neXtProt

NX_Q8NBT2

Antibodypedia

SPC24 antibodies


PROTEIN BROWSER

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ENST00000585486
 
ENST00000585567
 
ENST00000586708
 
ENST00000591396
 
ENST00000592540
 
ENST00000592967
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SPC24-001 ENSP00000465075
ENST00000592540
Q8NBT2
Show all »
Show » Show » 197 22.4 No 0
SPC24-004 ENSP00000465167
ENST00000585486
Show » 168 19 No 0
SPC24-005 ENSP00000465335
ENST00000592967
Show » 172 19.5 No 0
SPC24-006 ENSP00000466688
ENST00000591396
K7EMX1
Show all »
Show » 171 19.4 No 0
SPC24-007 ENSP00000468366
ENST00000586708
K7ERQ7
Show all »
Show » 126 13.6 No 0
SPC24-008 ENSP00000468818
ENST00000585567
K7ESQ2
Show all »
Show » 209 23.5 No 0