DBF4B

GENERAL INFORMATION

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Gene name

DBF4B

Gene description

DBF4 zinc finger B

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein localization

Moderate to strong cytoplasmic positivity with a granular pattern was displayed in gastrointestinal tract, gall bladder, thyroid, adrenal gland and prostate. Remaining normal tissues were negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA048465
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enriched (testis)

Organ

Expression



GENE INFORMATION

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Gene name

DBF4B (HGNC Symbol)

Synonyms

ASKL1, chifb, DRF1, FLJ13087, ZDBF1B

Description

DBF4 zinc finger B (HGNC Symbol)

Entrez gene summary

This gene encodes a regulator of the cell division cycle 7 homolog (S. cerevisiae) protein, a serine-threonine kinase which links cell cycle regulation to genome duplication. This protein localizes to the nucleus and, in complex with the cell division cycle 7 homolog (S. cerevisiae) protein, may facilitate M phase progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010]

Chromosome

17

Cytoband

q21.31

Chromosome location (bp)

44708608 - 44752264

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000161692 (version 78.38)

Entrez gene

80174

UniProt

Q8NFT6 (UniProt - Evidence at protein level)

neXtProt

NX_Q8NFT6

Antibodypedia

DBF4B antibodies


PROTEIN BROWSER

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ENST00000315005
 
ENST00000393547
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DBF4B-001 ENSP00000323663
ENST00000315005
Q8NFT6
Show all »
Show » Show » 615 67.2 No 0
DBF4B-003 ENSP00000377178
ENST00000393547
Q8NFT6
Show all »
Show » Show » 431 47.2 No 0