FAM189B

GENE INFORMATION

? »

Gene name

FAM189B (HGNC Symbol)

Synonyms

C1orf2, cote1

Description

Family with sequence similarity 189, member B (HGNC Symbol)

Entrez gene summary

This gene is located near the gene for the lysosomal enzyme glucosylceramidase; a deficiency in this enzyme is associated with Gaucher disease. The encoded protein has been identified as a potential binding partner of a WW domain-containing protein which is involved in apoptosis and tumor suppression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]

Chromosome

1

Cytoband

q22

Chromosome location (bp)

155247205 - 155255483

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000160767 (version 78.38)

Entrez gene

10712

UniProt

P81408 (UniProt - Evidence at protein level)

neXtProt

NX_P81408

Antibodypedia

FAM189B antibodies
 

PROTEIN VIEW

? »
 
 
 
FAM189B-001
 
FAM189B-002
 
FAM189B-004
 
FAM189B-008
 
FAM189B-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FAM189B-001 ENSP00000354958
ENST00000361361
P81408
Show all »
Show » Show » 668 71.4 No 4
FAM189B-002 ENSP00000307128
ENST00000350210
P81408
Show all »
Show » Show » 572 61.1 No 2
FAM189B-004 ENSP00000357352
ENST00000368368
P81408
Show all »
Show » Show » 650 69.4 No 3
FAM189B-008 ENSP00000427011
ENST00000491082
D6RD59
Show all »
Show » Show » 325 34.9 No 2
FAM189B-201 ENSP00000479323
ENST00000621094
Q96H71
Show all »
Show » Show » 242 26.1 No 2