CD3G

GENE INFORMATION

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Gene name

CD3G

Synonyms

Description

CD3g molecule, gamma (CD3-TCR complex) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

q23.3

Chromosome location (bp)

118344344 - 118355161

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000160654 (version 78.38)

Entrez gene

917

UniProt

P09693 (UniProt - Evidence at protein level)

neXtProt

NX_P09693

Antibodypedia

CD3G antibodies
 

PROTEIN VIEW

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CD3G-001
 
CD3G-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CD3G-001 ENSP00000431445
ENST00000532917
P09693
Show all »
Show » Show » 182 20.5 Yes 1
CD3G-201 ENSP00000376621
ENST00000392883
A8MUH3
Show all »
Show » Show » 78 9.2 No 0