DEDD2

GENE INFORMATION

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Gene name

DEDD2 (HGNC Symbol)

Synonyms

FLAME-3

Description

Death effector domain containing 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a nuclear-localized protein containing a death effector domain (DED). The encoded protein may regulate the trafficking of caspases and other proteins into the nucleus during death receptor-induced apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]

Chromosome

19

Cytoband

q13.2

Chromosome location (bp)

42198598 - 42220140

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000160570 (version 78.38)

Entrez gene

162989

UniProt

Q8WXF8 (UniProt - Evidence at protein level)

neXtProt

NX_Q8WXF8

Antibodypedia

DEDD2 antibodies
 

PROTEIN VIEW

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DEDD2-001
 
DEDD2-003
 
DEDD2-010
 
DEDD2-011
 
DEDD2-013
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DEDD2-001 ENSP00000470082
ENST00000595337
Q8WXF8
Show all »
Show » Show » 326 36.2 No 0
DEDD2-003 ENSP00000471512
ENST00000596251
Q8WXF8
Show all »
Show » Show » 326 36.2 No 0
DEDD2-010 ENSP00000469233
ENST00000598727
M0QXK7
Show all »
Show » Show » 204 22.6 No 0
DEDD2-011 ENSP00000336972
ENST00000336034
M0QYK9
Show all »
Show » Show » 321 35.6 No 0
DEDD2-013 ENSP00000469898
ENST00000598200
M0QYK9
Show all »
Show » Show » 118 13.2 No 0