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GENE INFORMATION
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The gene information section lists the gene name (HUGO Gene Nomenclature Committee ( HGNC) name if available), any approved gene synonyms, Ensembl gene description, and the Entrez gene summary from the National Center for Biotechnology Information.
The chromosomal and cytoband location of the gene according to Ensembl is reported together with the Ensembl gene identifier and Ensembl database version.
The Entrez gene identifier for the gene is also given. If any of the protein products of
the gene is linked to a UniProt KB/SWISS-PROT entry, links to the UniProt and the
neXtProt databases for these proteins are displayed.
There is also a link to the Antibodypedia portal where validation data for antibodies produced by other suppliers
against this gene can be found.
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Gene name |
ATP5G1 (HGNC Symbol) |
Synonyms |
ATP5G |
Description |
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) (HGNC Symbol) |
Entrez gene summary |
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene is one of three genes that encode subunit c of the proton channel. Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] |
Chromosome |
17 |
Cytoband |
q21.32 |
Chromosome location (bp) |
48892765 - 48895871 |
Protein evidence |
Evidence at transcript level (all genes) |
Ensembl |
ENSG00000159199 (version 78.38) |
Entrez gene |
516 |
UniProt |
P05496 (UniProt - Evidence at transcript level) |
neXtProt |
NX_P05496 |
Antibodypedia |
ATP5G1 antibodies |
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PROTEIN VIEW
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The protein view displays protein features. The tabs at the top of the protein view section can be used to switch between the different splice variants encoded by this gene. The mouse over function displays additional data for the features in the protein view.
At the top of the protein view, the maximum percent sequence identity of the protein to all other proteins from other human genes is shown, using a sliding window of 10 aa residues
(HsID 10) or 50 aa residues (HsID 50) ( read more).
If a signal peptide is predicted by a majority of the signal peptide predictors SPOCTOPUS,
SignalP 4.0, and
Phobius
(turquoise) and/or transmembrane regions (orange) are predicted by MDM, these are displayed.
Low complexity regions are shown in yellow and InterPro regions in green.
Common (purple) and unique (grey) regions between different splice variants of the gene are also displayed
( read more), and at the bottom of the protein view is the protein scale.
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PROTEIN INFORMATION
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The protein information section displays the alternative protein-coding transcripts (splice variants) encoded by this gene, according to the Ensembl database.
The ENSP identifier links to the Ensembl website protein summary, while the ENST identifier links to the Ensembl website transcript summary for the selected splice variant.
The data in the UniProt column can be expanded to show links to all matching
UniProt identifiers for this protein.
The protein classes to which this protein has been assigned are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.
The Gene Ontology terms assigned to this protein are listed if expanding the Gene ontology column.
The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide (according to a majority of the signal peptide predictors
SPOCTOPUS,
SignalP 4.0, and
Phobius) and the number of predicted transmembrane region(s) (according to
MDM) are also reported.
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Splice variant |
Ensembl |
UniProt |
Protein class |
Gene ontology |
Length (aa) |
Molecular mass (kDa) |
Signal peptide (predicted) |
Transmembrane regions (predicted)
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ATP5G1-001 |
ENSP00000348205
ENST00000355938
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P05496 Show all »
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P05496 [Direct mapping]ATP synthase F(0) complex subunit C1, mitochondrial Q6FIH7 [Target identity:100%; Query identity:100%]ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (Subunit 9), isoform CRA_a {ECO:0000313|EMBL:EAW94705.1}; ATP5G1 protein {ECO:0000313|EMBL:CAG38480.1}; cDNA, FLJ92113, Homo sapiens ATP synthase, H+ transporting, mitochondrial F0complex, subunit c (subunit 9), isoform 1 (ATP5G1), mRNA {ECO:0000313|EMBL:BAG34790.1} D6R9H7 [Target identity:72%; Query identity:100%]ATP synthase F(0) complex subunit C1, mitochondrial {ECO:0000313|Ensembl:ENSP00000422086} I3L0Y5 [Target identity:72%; Query identity:100%]ATP synthase F(0) complex subunit C1, mitochondrial {ECO:0000313|Ensembl:ENSP00000458423}
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Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Mitochondrial proteins
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GO:0005215 [transporter activity] GO:0005739 [mitochondrion] GO:0005743 [mitochondrial inner membrane] GO:0005753 [mitochondrial proton-transporting ATP synthase complex] GO:0008289 [lipid binding] GO:0015078 [hydrogen ion transmembrane transporter activity] GO:0015986 [ATP synthesis coupled proton transport] GO:0015991 [ATP hydrolysis coupled proton transport] GO:0016021 [integral component of membrane] GO:0022904 [respiratory electron transport chain] GO:0033177 [proton-transporting two-sector ATPase complex, proton-transporting domain] GO:0042776 [mitochondrial ATP synthesis coupled proton transport] GO:0044237 [cellular metabolic process] GO:0044281 [small molecule metabolic process] GO:0045263 [proton-transporting ATP synthase complex, coupling factor F(o)]
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136 |
14.3 |
No |
2 |
ATP5G1-003 |
ENSP00000377033
ENST00000393366
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P05496 Show all »
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P05496 [Direct mapping]ATP synthase F(0) complex subunit C1, mitochondrial Q6FIH7 [Target identity:100%; Query identity:100%]ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (Subunit 9), isoform CRA_a {ECO:0000313|EMBL:EAW94705.1}; ATP5G1 protein {ECO:0000313|EMBL:CAG38480.1}; cDNA, FLJ92113, Homo sapiens ATP synthase, H+ transporting, mitochondrial F0complex, subunit c (subunit 9), isoform 1 (ATP5G1), mRNA {ECO:0000313|EMBL:BAG34790.1} D6R9H7 [Target identity:72%; Query identity:100%]ATP synthase F(0) complex subunit C1, mitochondrial {ECO:0000313|Ensembl:ENSP00000422086} I3L0Y5 [Target identity:72%; Query identity:100%]ATP synthase F(0) complex subunit C1, mitochondrial {ECO:0000313|Ensembl:ENSP00000458423}
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Show »
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Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Mitochondrial proteins
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GO:0005215 [transporter activity] GO:0005739 [mitochondrion] GO:0005743 [mitochondrial inner membrane] GO:0005753 [mitochondrial proton-transporting ATP synthase complex] GO:0008289 [lipid binding] GO:0015078 [hydrogen ion transmembrane transporter activity] GO:0015986 [ATP synthesis coupled proton transport] GO:0015991 [ATP hydrolysis coupled proton transport] GO:0016021 [integral component of membrane] GO:0022904 [respiratory electron transport chain] GO:0033177 [proton-transporting two-sector ATPase complex, proton-transporting domain] GO:0042776 [mitochondrial ATP synthesis coupled proton transport] GO:0044237 [cellular metabolic process] GO:0044281 [small molecule metabolic process] GO:0045263 [proton-transporting ATP synthase complex, coupling factor F(o)]
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136 |
14.3 |
No |
2 |
ATP5G1-006 |
ENSP00000426094
ENST00000503641
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E7EPU7 Show all »
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E7EPU7 [Target identity:100%; Query identity:100%]ATP synthase F(0) complex subunit C1, mitochondrial {ECO:0000313|Ensembl:ENSP00000426094}
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Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM
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GO:0008289 [lipid binding] GO:0015078 [hydrogen ion transmembrane transporter activity] GO:0015986 [ATP synthesis coupled proton transport] GO:0015991 [ATP hydrolysis coupled proton transport] GO:0016021 [integral component of membrane] GO:0033177 [proton-transporting two-sector ATPase complex, proton-transporting domain] GO:0045263 [proton-transporting ATP synthase complex, coupling factor F(o)]
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127 |
13.2 |
No |
2 |
ATP5G1-007 |
ENSP00000422086
ENST00000514808
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D6R9H7 Show all »
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D6R9H7 [Target identity:100%; Query identity:100%]ATP synthase F(0) complex subunit C1, mitochondrial {ECO:0000313|Ensembl:ENSP00000422086} I3L0Y5 [Target identity:98%; Query identity:100%]ATP synthase F(0) complex subunit C1, mitochondrial {ECO:0000313|Ensembl:ENSP00000458423}
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SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins Predicted intracellular proteins
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Show »
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GO:0015078 [hydrogen ion transmembrane transporter activity] GO:0015986 [ATP synthesis coupled proton transport] GO:0015991 [ATP hydrolysis coupled proton transport] GO:0033177 [proton-transporting two-sector ATPase complex, proton-transporting domain] GO:0045263 [proton-transporting ATP synthase complex, coupling factor F(o)]
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99 |
10.2 |
No |
0 |
ATP5G1-008 |
ENSP00000422950
ENST00000506855
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E7EQ97 Show all »
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E7EQ97 [Target identity:100%; Query identity:100%]ATP synthase F(0) complex subunit C1, mitochondrial {ECO:0000313|Ensembl:ENSP00000422950}
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Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM
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Show »
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GO:0008289 [lipid binding] GO:0015078 [hydrogen ion transmembrane transporter activity] GO:0015986 [ATP synthesis coupled proton transport] GO:0015991 [ATP hydrolysis coupled proton transport] GO:0016021 [integral component of membrane] GO:0033177 [proton-transporting two-sector ATPase complex, proton-transporting domain] GO:0045263 [proton-transporting ATP synthase complex, coupling factor F(o)]
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110 |
11.5 |
No |
2 |
ATP5G1-010 |
ENSP00000458423
ENST00000504591
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I3L0Y5 Show all »
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I3L0Y5 [Target identity:100%; Query identity:100%]ATP synthase F(0) complex subunit C1, mitochondrial {ECO:0000313|Ensembl:ENSP00000458423}
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Show »
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SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins Predicted intracellular proteins
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Show »
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GO:0015078 [hydrogen ion transmembrane transporter activity] GO:0015986 [ATP synthesis coupled proton transport] GO:0015991 [ATP hydrolysis coupled proton transport] GO:0033177 [proton-transporting two-sector ATPase complex, proton-transporting domain] GO:0045263 [proton-transporting ATP synthase complex, coupling factor F(o)]
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98 |
10 |
No |
0 |
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