KCNE2

GENE INFORMATION

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Gene name

KCNE2 (HGNC Symbol)

Synonyms

LQT6, MiRP1

Description

Potassium voltage-gated channel, Isk-related family, member 2 (HGNC Symbol)

Entrez gene summary

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a small integral membrane subunit that assembles with the KCNH2 gene product, a pore-forming protein, to alter its function. This gene is expressed in heart and muscle and the gene mutations are associated with cardiac arrhythmia. [provided by RefSeq, Jul 2008]

Chromosome

21

Cytoband

q22.11

Chromosome location (bp)

34364024 - 34371389

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000159197 (version 78.38)

Entrez gene

9992

UniProt

Q9Y6J6 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y6J6

Antibodypedia

KCNE2 antibodies
 

PROTEIN VIEW

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KCNE2-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KCNE2-001 ENSP00000290310
ENST00000290310
Q9Y6J6
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