IFNGR2

GENE INFORMATION

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Gene name

IFNGR2 (HGNC Symbol)

Synonyms

AF-1, IFNGT1

Description

Interferon gamma receptor 2 (interferon gamma transducer 1) (HGNC Symbol)

Entrez gene summary

This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance. [provided by RefSeq, Jul 2008]

Chromosome

21

Cytoband

q22.11

Chromosome location (bp)

33402896 - 33479348

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000159128 (version 78.38)

Entrez gene

3460

UniProt

P38484 (UniProt - Evidence at protein level)

neXtProt

NX_P38484

Antibodypedia

IFNGR2 antibodies
 

PROTEIN VIEW

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IFNGR2-001
 
IFNGR2-002
 
IFNGR2-005
 
IFNGR2-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IFNGR2-001 ENSP00000290219
ENST00000290219
P38484
Show all »
Show » Show » 337 37.8 Yes 1
IFNGR2-002 ENSP00000371425
ENST00000381995
E7EUY1
Show all »
Show » Show » 356 40 Yes 1
IFNGR2-005 ENSP00000402629
ENST00000421802
Show » 60 6.6 No 1
IFNGR2-007 ENSP00000385044
ENST00000405436
B5MCZ0
Show all »
Show » Show » 258 29 No 1