CDC25C

GENE INFORMATION

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Gene name

CDC25C (HGNC Symbol)

Synonyms

CDC25, PPP1R60

Description

Cell division cycle 25C (HGNC Symbol)

Entrez gene summary

This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. [provided by RefSeq, Jul 2008]

Chromosome

5

Cytoband

q31.2

Chromosome location (bp)

138285265 - 138338355

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000158402 (version 78.38)

Entrez gene

995

UniProt

P30307 (UniProt - Evidence at protein level)

neXtProt

NX_P30307

Antibodypedia

CDC25C antibodies
 

PROTEIN VIEW

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CDC25C-001
 
CDC25C-002
 
CDC25C-003
 
CDC25C-004
 
CDC25C-005
 
CDC25C-006
 
CDC25C-007
 
CDC25C-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDC25C-001 ENSP00000321656
ENST00000323760
P30307
Show all »
Show » Show » 473 53.4 No 0
CDC25C-002 ENSP00000392631
ENST00000415130
P30307
Show all »
Show » Show » 400 45.6 No 0
CDC25C-003 ENSP00000424795
ENST00000513970
P30307
Show all »
Show » Show » 473 53.4 No 0
CDC25C-004 ENSP00000425470
ENST00000514555
P30307
Show all »
Show » Show » 443 50.1 No 0
CDC25C-005 ENSP00000427251
ENST00000503022
D6RJC2
Show all »
Show » Show » 249 27.3 No 0
CDC25C-006 ENSP00000427105
ENST00000510119
D6RD20
Show all »
Show » Show » 170 18.3 No 0
CDC25C-007 ENSP00000423525
ENST00000514017
Show » Show » 258 30 No 0
CDC25C-201 ENSP00000345205
ENST00000348983
P30307
Show all »
Show » Show » 400 45.6 No 0