CUL4B

GENE INFORMATION

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Gene name

CUL4B

Synonyms

Description

Cullin 4B (HGNC Symbol)

Entrez gene summary

This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

X

Cytoband

q24

Chromosome location (bp)

120524609 - 120575794

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000158290 (version 78.38)

Entrez gene

8450

UniProt

Q13620 (UniProt - Evidence at protein level)

neXtProt

NX_Q13620

Antibodypedia

CUL4B antibodies
 

PROTEIN VIEW

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CUL4B-001
 
CUL4B-003
 
CUL4B-004
 
CUL4B-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CUL4B-001 ENSP00000384109
ENST00000404115
Q13620
Show all »
Show » Show » 913 104 No 0
CUL4B-003 ENSP00000360373
ENST00000371322
Q13620
Show all »
Show » Show » 895 102.3 No 0
CUL4B-004 ENSP00000338919
ENST00000336592
K4DI93
Show all »
Show » Show » 900 102.8 No 0
CUL4B-007 ENSP00000360374
ENST00000371323
A6NE76
Show all »
Show » Show » 234 27.9 No 0