MAGEA8

GENE INFORMATION

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Gene name

MAGEA8 (HGNC Symbol)

Synonyms

CT1.8, MAGE8, MGC2182

Description

Melanoma antigen family A, 8 (HGNC Symbol)

Entrez gene summary

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Oct 2009]

Chromosome

X

Cytoband

q28

Chromosome location (bp)

149881141 - 149885835

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000156009 (version 78.38)

Entrez gene

4107

UniProt

P43361 (UniProt - Evidence at transcript level)

neXtProt

NX_P43361

Antibodypedia

MAGEA8 antibodies
 

PROTEIN VIEW

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MAGEA8-001
 
MAGEA8-201
 
MAGEA8-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MAGEA8-001 ENSP00000286482
ENST00000286482
P43361
Show all »
Show » Show » 318 35.2 No 0
MAGEA8-201 ENSP00000438293
ENST00000535454
P43361
Show all »
Show » Show » 318 35.2 No 0
MAGEA8-202 ENSP00000443776
ENST00000542674
P43361
Show all »
Show » Show » 318 35.2 No 0