ELMO1

GENERAL INFORMATION

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Gene name

ELMO1

Gene description

Engulfment and cell motility 1

Protein class

Cytoskeleton related proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

11
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

ANTIBODY RELIABILITY

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Data reliability

Pending normal tissue annotation.
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A


PROTEIN EXPRESSION OVERVIEW

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Pending normal tissue annotation.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

ELMO1 (HGNC Symbol)

Synonyms

CED-12, CED12, ELMO-1, KIAA0281

Description

Engulfment and cell motility 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Chromosome

7

Cytoband

Chromosome location (bp)

36854361 - 37449249

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000155849 (version 78.38)

Entrez gene

9844

UniProt

Q92556 (UniProt - Evidence at protein level)

neXtProt

NX_Q92556

Antibodypedia

ELMO1 antibodies


PROTEIN BROWSER

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 « 
 
ENST00000310758
 
ENST00000396040
 
ENST00000396045
 
ENST00000424212
 
ENST00000433246
 
ENST00000442504
 
ENST00000445322
 
ENST00000448602
 
ENST00000453399
 
ENST00000455119
 
ENST00000455879
 
 » 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ELMO1-001 ENSP00000312185
ENST00000310758
Q92556
Show all »
Show » Show » 727 83.8 No 0
ELMO1-002 ENSP00000379360
ENST00000396045
Q92556
Show all »
Show » Show » 247 28.7 No 0
ELMO1-003 ENSP00000394458
ENST00000448602
Q92556
Show all »
Show » Show » 727 83.8 No 0
ELMO1-005 ENSP00000397857
ENST00000445322
C9J5X3
Show all »
Show » 59 6.6 No 0
ELMO1-006 ENSP00000391734
ENST00000453399
C9JB20
Show all »
Show » 81 9.2 No 0
ELMO1-007 ENSP00000416090
ENST00000455879
C9JIW2
Show all »
Show » Show » 149 16.8 No 0
ELMO1-008 ENSP00000406952
ENST00000442504
Q92556
Show all »
Show » Show » 727 83.8 No 0
ELMO1-012 ENSP00000406610
ENST00000455119
C9IZR8
Show all »
Show » Show » 167 18.6 No 0
ELMO1-013 ENSP00000413108
ENST00000433246
Show » Show » 194 22.4 No 0
ELMO1-014 ENSP00000395933
ENST00000424212
H7C0N5
Show all »
Show » Show » 124 14.1 No 0
ELMO1-019 ENSP00000379355
ENST00000396040
Q92556
Show all »
Show » Show » 247 28.7 No 0