ATP5J

GENE INFORMATION

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Gene name

ATP5J (HGNC Symbol)

Synonyms

ATP5, ATP5A, ATPM, CF6

Description

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 (HGNC Symbol)

Entrez gene summary

Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the F6 subunit of the Fo complex, required for F1 and Fo interactions. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. A pseudogene exists on chromosome Yp11.[provided by RefSeq, Jun 2010]

Chromosome

21

Cytoband

q21.3

Chromosome location (bp)

25716503 - 25735673

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000154723 (version 78.38)

Entrez gene

522

UniProt

P18859 (UniProt - Evidence at protein level)

neXtProt

NX_P18859

Antibodypedia

ATP5J antibodies
 

PROTEIN VIEW

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ATP5J-001
 
ATP5J-002
 
ATP5J-003
 
ATP5J-004
 
ATP5J-005
 
ATP5J-006
 
ATP5J-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ATP5J-001 ENSP00000284971
ENST00000284971
P18859
Show all »
Show » Show » 108 12.6 No 0
ATP5J-002 ENSP00000382965
ENST00000400093
P18859
Show all »
Show » Show » 108 12.6 No 0
ATP5J-003 ENSP00000389649
ENST00000457143
P18859
Show all »
Show » Show » 116 13.4 No 0
ATP5J-004 ENSP00000382971
ENST00000400099
A8MUH2
Show all »
Show » Show » 119 14 No 0
ATP5J-005 ENSP00000382962
ENST00000400090
P18859
Show all »
Show » Show » 108 12.6 No 0
ATP5J-006 ENSP00000382959
ENST00000400087
P18859
Show all »
Show » Show » 108 12.6 No 0
ATP5J-007 ENSP00000382966
ENST00000400094
P18859
Show all »
Show » Show » 108 12.6 No 0