DISP1

GENE INFORMATION

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Gene name

DISP1 (HGNC Symbol)

Synonyms

DISPA, DKFZP434I0428, MGC13130, MGC16796

Description

Dispatched homolog 1 (Drosophila) (HGNC Symbol)

Entrez gene summary

The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

q41

Chromosome location (bp)

222872271 - 223005995

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000154309 (version 78.38)

Entrez gene

84976

UniProt

Q96F81 (UniProt - Evidence at transcript level)

neXtProt

NX_Q96F81

Antibodypedia

DISP1 antibodies
 

PROTEIN VIEW

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DISP1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DISP1-001 ENSP00000284476
ENST00000284476
Q96F81
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