PLA2R1

GENERAL INFORMATION

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Gene name

PLA2R1

Gene description

Phospholipase A2 receptor 1, 180kDa

Protein class

Predicted membrane proteins
Predicted secreted proteins

Predicted localization

Membrane,Secreted

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (thyroid gland)
GTEx:Tissue enhanced (thyroid gland)

Protein evidence

Evidence at protein level

Protein localization

Selective expression in renal glomeruli.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 3 antibodies.
HPA012657 , CAB068217 , CAB068218
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (thyroid gland)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (thyroid gland)

Organ

Expression



GENE INFORMATION

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Gene name

PLA2R1 (HGNC Symbol)

Synonyms

CLEC13C, PLA2-R, PLA2G1R, PLA2IR

Description

Phospholipase A2 receptor 1, 180kDa (HGNC Symbol)

Entrez gene summary

This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Sep 2010]

Chromosome

2

Cytoband

q24.2

Chromosome location (bp)

159932006 - 160062610

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000153246 (version 78.38)

Entrez gene

22925

UniProt

Q13018 (UniProt - Evidence at protein level)

neXtProt

NX_Q13018

Antibodypedia

PLA2R1 antibodies


PROTEIN BROWSER

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ENST00000283243
 
ENST00000392771
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PLA2R1-001 ENSP00000283243
ENST00000283243
Q13018
Show all »
Show » Show » 1463 168.6 Yes 1
PLA2R1-002 ENSP00000376524
ENST00000392771
Q13018
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Show » Show » 1324 152.8 Yes 0