PANK1

GENE INFORMATION

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Gene name

PANK1 (HGNC Symbol)

Synonyms

MGC24596, PANK, PANK1a, PANK1b

Description

Pantothenate kinase 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the pantothenate kinase family. Pantothenate kinases are key regulatory enzymes in the biosynthesis of coenzyme A (CoA). The encoded protein catalyzes the first and rate-limiting enzymatic reaction in CoA biosynthesis and is regulated by CoA through feedback inhibition. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. This gene and an intronic miRNA on the same strand are co-regulated by the tumor suppressor p53 (see PMID 20833636). [provided by RefSeq, Apr 2011]

Chromosome

10

Cytoband

q23.31

Chromosome location (bp)

89579497 - 89645572

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000152782 (version 78.38)

Entrez gene

53354

UniProt

Q8TE04 (UniProt - Evidence at protein level)

neXtProt

NX_Q8TE04

Antibodypedia

PANK1 antibodies
 

PROTEIN VIEW

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PANK1-001
 
PANK1-002
 
PANK1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PANK1-001 ENSP00000345118
ENST00000342512
Q8TE04
Show all »
Show » Show » 373 41.7 No 0
PANK1-002 ENSP00000318526
ENST00000322191
Q8TE04
Show all »
Show » Show » 314 35.6 No 0
PANK1-201 ENSP00000302108
ENST00000307534
Q8TE04
Show all »
Show » Show » 598 64.3 No 0