DDX4

GENE INFORMATION

? »

Gene name

DDX4 (HGNC Symbol)

Synonyms

VASA

Description

DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 (HGNC Symbol)

Entrez gene summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a homolog of VASA proteins in Drosophila and several other species. The gene is specifically expressed in the germ cell lineage in both sexes and functions in germ cell development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

Chromosome

5

Cytoband

q11.2

Chromosome location (bp)

55738017 - 55817157

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000152670 (version 78.38)

Entrez gene

54514

UniProt

Q9NQI0 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NQI0

Antibodypedia

DDX4 antibodies
 

PROTEIN VIEW

? »
 
 
 
DDX4-001
 
DDX4-002
 
DDX4-003
 
DDX4-005
 
DDX4-006
 
DDX4-007
 
DDX4-008
 
DDX4-009
 
DDX4-201
 
DDX4-202
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DDX4-001 ENSP00000424838
ENST00000505374
Q9NQI0
Show all »
Show » Show » 724 79.3 No 0
DDX4-002 ENSP00000427167
ENST00000506511
D6RCM4
Show all »
Show » Show » 518 56.5 No 0
DDX4-003 ENSP00000347087
ENST00000354991
Q9NQI0
Show all »
Show » Show » 690 75.8 No 0
DDX4-005 ENSP00000423123
ENST00000511853
Q9NQI0
Show all »
Show » Show » 575 63.2 No 0
DDX4-006 ENSP00000421960
ENST00000506848
D6RAF5
Show all »
Show » 105 11.6 No 0
DDX4-007 ENSP00000424112
ENST00000514679
D6RBL3
Show all »
Show » 159 17.5 No 0
DDX4-008 ENSP00000427522
ENST00000511491
D6RIB2
Show all »
Show » 156 17.3 No 0
DDX4-009 ENSP00000424779
ENST00000515709
D6RAT7
Show all »
Show » 142 15.5 No 0
DDX4-201 ENSP00000334167
ENST00000353507
Q9NQI0
Show all »
Show » Show » 690 75.8 No 0
DDX4-202 ENSP00000425359
ENST00000514278
Q9NQI0
Show all »
Show » Show » 704 77.1 No 0