GUCY1A2

GENE INFORMATION

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Gene name

GUCY1A2 (HGNC Symbol)

Synonyms

GC-SA2, GUC1A2

Description

Guanylate cyclase 1, soluble, alpha 2 (HGNC Symbol)

Entrez gene summary

Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Chromosome

11

Cytoband

q22.3

Chromosome location (bp)

106674012 - 107018524

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000152402 (version 78.38)

Entrez gene

2977

UniProt

P33402 (UniProt - Evidence at protein level)

neXtProt

NX_P33402

Antibodypedia

GUCY1A2 antibodies
 

PROTEIN VIEW

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GUCY1A2-001
 
GUCY1A2-002
 
GUCY1A2-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GUCY1A2-001 ENSP00000431245
ENST00000526355
P33402
Show all »
Show » Show » 732 81.7 No 0
GUCY1A2-002 ENSP00000282249
ENST00000282249
P33402
Show all »
Show » Show » 763 85.3 No 0
GUCY1A2-003 ENSP00000344874
ENST00000347596
P33402
Show all »
Show » Show » 753 84 No 0