TCF7L1

GENE INFORMATION

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Gene name

TCF7L1 (HGNC Symbol)

Synonyms

TCF3

Description

Transcription factor 7-like 1 (T-cell specific, HMG-box) (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway and are antagonized by the transforming growth factor beta signaling pathway. The encoded protein contains a high mobility group-box DNA binding domain and participates in the regulation of cell cycle genes and cellular senescence. [provided by RefSeq, Nov 2010]

Chromosome

2

Cytoband

p11.2

Chromosome location (bp)

85133410 - 85310388

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000152284 (version 78.38)

Entrez gene

83439

UniProt

Q9HCS4 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9HCS4

Antibodypedia

TCF7L1 antibodies
 

PROTEIN VIEW

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TCF7L1-001
 
TCF7L1-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TCF7L1-001 ENSP00000282111
ENST00000282111
Q9HCS4
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Show » Show » 588 62.6 No 0
TCF7L1-004 ENSP00000388984
ENST00000442813
C9JPE3
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Show » 29 3.2 No 0