PTPN14

GENE INFORMATION

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Gene name

PTPN14 (HGNC Symbol)

Synonyms

PEZ

Description

Protein tyrosine phosphatase, non-receptor type 14 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia. [provided by RefSeq, Sep 2010]

Chromosome

1

Cytoband

Chromosome location (bp)

214348696 - 214552449

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000152104 (version 78.38)

Entrez gene

5784

UniProt

Q15678 (UniProt - Evidence at protein level)

neXtProt

NX_Q15678

Antibodypedia

PTPN14 antibodies
 

PROTEIN VIEW

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PTPN14-001
 
PTPN14-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PTPN14-001 ENSP00000355923
ENST00000366956
Q15678
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Show » Show » 1187 135.3 No 0
PTPN14-201 ENSP00000443330
ENST00000543945
E2J9M0
Show all »
Show » Show » 211 24.9 No 0