DST

GENE INFORMATION

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Gene name

DST (HGNC Symbol)

Synonyms

BP240, BPA, BPAG1, CATX-15, FLJ13425, FLJ21489, FLJ30627, FLJ32235, KIAA0728, MACF2

Description

Dystonin (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the plakin protein family of adhesion junction plaque proteins. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the full-length nature of some variants has not been defined. It has been reported that some isoforms are expressed in neural and muscle tissue, anchoring neural intermediate filaments to the actin cytoskeleton, and some isoforms are expressed in epithelial tissue, anchoring keratin-containing intermediate filaments to hemidesmosomes. Consistent with the expression, mice defective for this gene show skin blistering and neurodegeneration. [provided by RefSeq, Mar 2010]

Chromosome

6

Cytoband

p12.1

Chromosome location (bp)

56457987 - 56954628

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000151914 (version 78.38)

Entrez gene

667

UniProt

Q03001 (UniProt - Evidence at protein level)

neXtProt

NX_Q03001

Antibodypedia

DST antibodies
 

PROTEIN VIEW

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 « 
 
DST-001
 
DST-004
 
DST-005
 
DST-009
 
DST-010
 
DST-011
 
DST-012
 
DST-015
 
DST-018
 
DST-022
 
DST-024
 
DST-026
 
DST-031
 
DST-201
 
DST-202
 
DST-203
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DST-001 ENSP00000359824
ENST00000370788
E7ERU0
Show all »
Show » Show » 5375 615.7 No 0
DST-004 ENSP00000354508
ENST00000361203
F8W9J4
Show all »
Show » Show » 7461 848 No 0
DST-005 ENSP00000244364
ENST00000244364
Q03001
Show all »
Show » Show » 5171 591 No 0
DST-009 ENSP00000393082
ENST00000449297
Q5T0V7
Show all »
Show » Show » 689 79.2 No 0
DST-010 ENSP00000359801
ENST00000370765
Q03001
Show all »
Show » Show » 2649 306.8 No 0
DST-011 ENSP00000404924
ENST00000439203
Q03001
Show all »
Show » Show » 3060 345 No 0
DST-012 ENSP00000431030
ENST00000520645
E7ETB9
Show all »
Show » Show » 1479 171.5 No 0
DST-015 ENSP00000431003
ENST00000518935
Q6P0N6
Show all »
Show » Show » 1143 132.3 No 0
DST-018 ENSP00000431020
ENST00000523292
Q9BSP9
Show all »
Show » Show » 259 27.8 No 0
DST-022 ENSP00000429221
ENST00000523817
E7ERX3
Show all »
Show » Show » 154 18.2 No 0
DST-024 ENSP00000429075
ENST00000522538
E7ESK0
Show all »
Show » Show » 133 15.6 No 0
DST-026 ENSP00000428068
ENST00000522360
Show » 177 20.6 No 0
DST-031 ENSP00000430472
ENST00000523943
H0YBX0
Show all »
Show » 123 14.3 No 0
DST-201 ENSP00000307959
ENST00000312431
E7ETB9
Show all »
Show » Show » 5537 633.7 No 0
DST-202 ENSP00000359790
ENST00000370754
Q5T0V7
Show all »
Show » Show » 5675 649.5 Yes 0
DST-203 ENSP00000400883
ENST00000421834
Q86T18
Show all »
Show » Show » 5497 629.8 No 0