SLC25A4

GENE INFORMATION

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Gene name

SLC25A4 (HGNC Symbol)

Synonyms

ANT1, PEO2, PEO3, T1

Description

Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 (HGNC Symbol)

Entrez gene summary

This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Mutations in this gene have been shown to result in autosomal dominant progressive external opthalmoplegia and familial hypertrophic cardiomyopathy. [provided by RefSeq, Jun 2013]

Chromosome

4

Cytoband

q35.1

Chromosome location (bp)

185143241 - 185150382

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000151729 (version 78.38)

Entrez gene

291

UniProt

P12235 (UniProt - Evidence at protein level)

neXtProt

NX_P12235

Antibodypedia

SLC25A4 antibodies
 

PROTEIN VIEW

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SLC25A4-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC25A4-001 ENSP00000281456
ENST00000281456
P12235
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