FLI1

GENERAL INFORMATION

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Gene name

FLI1

Gene description

Fli-1 proto-oncogene, ETS transcription factor

Protein class

Cancer-related genes
Disease related genes
Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

ANTIBODY RELIABILITY

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Data reliability

Pending normal tissue annotation.
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A


PROTEIN EXPRESSION OVERVIEW

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Pending normal tissue annotation.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

FLI1 (HGNC Symbol)

Synonyms

EWSR2, SIC-1

Description

Fli-1 proto-oncogene, ETS transcription factor (HGNC Symbol)

Entrez gene summary

This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Chromosome

11

Cytoband

q24.3

Chromosome location (bp)

128686535 - 128813267

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000151702 (version 78.38)

Entrez gene

2313

UniProt

Q01543 (UniProt - Evidence at protein level)

neXtProt

NX_Q01543

Antibodypedia

FLI1 antibodies


PROTEIN BROWSER

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ENST00000281428
 
ENST00000344954
 
ENST00000527767
 
ENST00000527786
 
ENST00000534087
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FLI1-001 ENSP00000433488
ENST00000527786
Q01543
Show all »
Show » Show » 452 51 No 0
FLI1-003 ENSP00000432950
ENST00000534087
Q01543
Show all »
Show » Show » 419 47.6 No 0
FLI1-008 ENSP00000476428
ENST00000527767
V9GY62
Show all »
Show » 106 11.9 No 0
FLI1-201 ENSP00000281428
ENST00000281428
Q01543
Show all »
Show » Show » 386 43.6 No 0
FLI1-202 ENSP00000339627
ENST00000344954
Q01543
Show all »
Show » Show » 259 29.1 No 0