SAP18

GENE INFORMATION

? »

Gene name

SAP18 (HGNC Symbol)

Synonyms

2HOR0202, MGC27131, SAP18p

Description

Sin3A-associated protein, 18kDa (HGNC Symbol)

Entrez gene summary

Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2. [provided by RefSeq, Dec 2008]

Chromosome

13

Cytoband

q12.11

Chromosome location (bp)

21140514 - 21149084

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000150459 (version 78.38)

Entrez gene

10284

UniProt

O00422 (UniProt - Evidence at protein level)

neXtProt

NX_O00422

Antibodypedia

SAP18 antibodies
 

PROTEIN VIEW

? »
 
 
 
SAP18-001
 
SAP18-005
 
SAP18-006
 
SAP18-008
 
SAP18-009
 
SAP18-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SAP18-001 ENSP00000371973
ENST00000382533
X6RAL5
Show all »
Show » Show » 172 19.5 No 0
SAP18-005 ENSP00000475358
ENST00000467636
U3KPY7
Show all »
Show » 78 9.1 No 0
SAP18-006 ENSP00000475435
ENST00000492245
Show » 59 6.8 No 0
SAP18-008 ENSP00000391846
ENST00000450573
H7BZW6
Show all »
Show » Show » 143 16 No 0
SAP18-009 ENSP00000475925
ENST00000607003
O00422
Show all »
Show » Show » 153 17.6 No 0
SAP18-201 ENSP00000481842
ENST00000621421
X6RAL5
Show all »
Show » Show » 172 19.5 No 0