DSN1

GENERAL INFORMATION

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Gene name

DSN1

Gene description

DSN1, MIS12 kinetochore complex component

Protein class

Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

7
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

General nuclear expression.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining consistent with RNA expression data.

Data reliability

Supportive based on 1 antibody.
HPA002813
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

DSN1 (HGNC Symbol)

Synonyms

C20orf172, dJ469A13.2, hKNL-3, KNL3, MIS13

Description

DSN1, MIS12 kinetochore complex component (HGNC Symbol)

Entrez gene summary

This gene encodes a kinetochore protein that functions as part of the minichromosome instability-12 centromere complex. The encoded protein is required for proper kinetochore assembly and progression through the cell cycle. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009]

Chromosome

20

Cytoband

q11.23

Chromosome location (bp)

36751791 - 36773818

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000149636 (version 78.38)

Entrez gene

79980

UniProt

Q9H410 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H410

Antibodypedia

DSN1 antibodies


PROTEIN BROWSER

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ENST00000373734
 
ENST00000373740
 
ENST00000373750
 
ENST00000426836
 
ENST00000438549
 
ENST00000447406
 
ENST00000448110
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DSN1-001 ENSP00000362855
ENST00000373750
Q9H410
Show all »
Show » Show » 356 40.1 No 0
DSN1-003 ENSP00000362845
ENST00000373740
Q5JW54
Show all »
Show » Show » 284 32.2 No 0
DSN1-004 ENSP00000399654
ENST00000447406
Q5JW53
Show all »
Show » Show » 241 27.3 No 0
DSN1-006 ENSP00000404463
ENST00000448110
Q9H410
Show all »
Show » Show » 340 38.3 No 0
DSN1-007 ENSP00000395760
ENST00000438549
Q5JW57
Show all »
Show » Show » 141 16.1 No 0
DSN1-009 ENSP00000362839
ENST00000373734
Q9H410
Show all »
Show » Show » 249 28 No 0
DSN1-201 ENSP00000389810
ENST00000426836
Q9H410
Show all »
Show » Show » 356 40.1 No 0