FADS1 - Gene info - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. Don't show this again.

FADS1

TISSUE

SUBCELL

CELL LINE

CANCER

GENE INFORMATION

? »

Gene name	FADS1 (HGNC Symbol)
Synonyms	D5D, FADS6, FADSD5, LLCDL1, TU12
Description	Fatty acid desaturase 1 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. [provided by RefSeq, Jul 2008]
Chromosome	11
Cytoband	q12.2
Chromosome location (bp)	61799625 - 61829318
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000149485 (version 78.38)
Entrez gene	3992
UniProt	O60427 (UniProt - Evidence at protein level)
neXtProt	NX_O60427
Antibodypedia	FADS1 antibodies

PROTEIN VIEW

? »

FADS1-001		FADS1-002		FADS1-004		FADS1-005		FADS1-006		FADS1-007		FADS1-009		FADS1-010		FADS1-012		FADS1-013		FADS1-014		FADS1-016		FADS1-017		FADS1-018		FADS1-019		FADS1-020		FADS1-022

PROTEIN INFORMATION

? »

Splice variant	Ensembl	UniProt	Protein class	Gene ontology	Length (aa)	Molecular mass (kDa)	Signal peptide (predicted)	Transmembrane regions (predicted)
FADS1-001	ENSP00000322229 ENST00000350997	F5H852 Show all » « Hide F5H852 [Target identity:32%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000442170} F5GYH4 [Target identity:30%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000440652} F5H3P6 [Target identity:29%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000445253} C9JJB3 [Target identity:27%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000416043} F5H8G5 [Target identity:24%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000443587} F5H5X5 [Target identity:22%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000443037} F5H2H3 [Target identity:21%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000446270} F5H0Y2 [Target identity:21%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000439790} F5H1Q7 [Target identity:17%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000438997} I3ZNN6 [Target identity:11%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91640.1} I3ZNT3 [Target identity:11%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91687.1} I3ZNS3 [Target identity:10%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91677.1} C9J425 [Target identity:9%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000391229} I3ZNS1 [Target identity:9%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91675.1} I3ZNH3 [Target identity:7%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91577.1} I3ZNL2 [Target identity:7%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91616.1} I3ZNL9 [Target identity:7%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91623.1} I3ZNS6 [Target identity:6%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91680.1} I3ZNE3 [Target identity:4%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91547.1}	Show » « Hide Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000248 [C-5 sterol desaturase activity] GO:0005506 [iron ion binding] GO:0005634 [nucleus] GO:0005739 [mitochondrion] GO:0005789 [endoplasmic reticulum membrane] GO:0006355 [regulation of transcription, DNA-templated] GO:0006629 [lipid metabolic process] GO:0006633 [fatty acid biosynthetic process] GO:0006636 [unsaturated fatty acid biosynthetic process] GO:0007267 [cell-cell signaling] GO:0007568 [aging] GO:0007584 [response to nutrient] GO:0008654 [phospholipid biosynthetic process] GO:0009267 [cellular response to starvation] GO:0009744 [response to sucrose] GO:0010033 [response to organic substance] GO:0014070 [response to organic cyclic compound] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016491 [oxidoreductase activity] GO:0016717 [oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water] GO:0019369 [arachidonic acid metabolic process] GO:0020037 [heme binding] GO:0032868 [response to insulin] GO:0033189 [response to vitamin A] GO:0033559 [unsaturated fatty acid metabolic process] GO:0035900 [response to isolation stress] GO:0036109 [alpha-linolenic acid metabolic process] GO:0043231 [intracellular membrane-bounded organelle] GO:0043651 [linoleic acid metabolic process] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0045595 [regulation of cell differentiation] GO:0046456 [icosanoid biosynthetic process] GO:0055114 [oxidation-reduction process]	501	57.9	No	5
FADS1-002	ENSP00000405087 ENST00000433932	O60427 Show all » « Hide O60427 [Direct mapping] Fatty acid desaturase 1 F5H852 [Target identity:45%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000442170} F5GYH4 [Target identity:42%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000440652} F5H3P6 [Target identity:40%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000445253} C9JJB3 [Target identity:38%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000416043} F5H8G5 [Target identity:34%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000443587} F5H5X5 [Target identity:31%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000443037} F5H2H3 [Target identity:30%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000446270} F5H0Y2 [Target identity:30%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000439790} F5H1Q7 [Target identity:23%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000438997} I3ZNN6 [Target identity:16%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91640.1} I3ZNS3 [Target identity:15%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91677.1} I3ZNT3 [Target identity:15%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91687.1} C9J425 [Target identity:13%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000391229} I3ZNS1 [Target identity:12%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91675.1} I3ZNL2 [Target identity:11%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91616.1} I3ZNH3 [Target identity:10%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91577.1} I3ZNL9 [Target identity:10%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91623.1} I3ZNS6 [Target identity:8%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91680.1} I3ZNE3 [Target identity:6%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91547.1}	Show » « Hide Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000248 [C-5 sterol desaturase activity] GO:0005506 [iron ion binding] GO:0005739 [mitochondrion] GO:0005789 [endoplasmic reticulum membrane] GO:0006355 [regulation of transcription, DNA-templated] GO:0006629 [lipid metabolic process] GO:0006636 [unsaturated fatty acid biosynthetic process] GO:0007267 [cell-cell signaling] GO:0008654 [phospholipid biosynthetic process] GO:0009267 [cellular response to starvation] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016491 [oxidoreductase activity] GO:0020037 [heme binding] GO:0033559 [unsaturated fatty acid metabolic process] GO:0036109 [alpha-linolenic acid metabolic process] GO:0043231 [intracellular membrane-bounded organelle] GO:0043651 [linoleic acid metabolic process] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0045595 [regulation of cell differentiation] GO:0046456 [icosanoid biosynthetic process] GO:0055114 [oxidation-reduction process]	360	42.5	No	4
FADS1-004	ENSP00000445253 ENST00000460649	F5H3P6 Show all » « Hide F5H3P6 [Target identity:100%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000445253} I3ZNE3 [Target identity:15%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91547.1}	Show » « Hide Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0006629 [lipid metabolic process]	146	17.3	No	1
FADS1-005	ENSP00000416043 ENST00000421879	C9JJB3 Show all » « Hide C9JJB3 [Target identity:100%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000416043} F5H5X5 [Target identity:80%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000443037} F5H2H3 [Target identity:79%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000446270} F5H0Y2 [Target identity:78%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000439790} F5H1Q7 [Target identity:61%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000438997} I3ZNN6 [Target identity:41%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91640.1} I3ZNT3 [Target identity:41%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91687.1} I3ZNS3 [Target identity:39%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91677.1} C9J425 [Target identity:33%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000391229} I3ZNS1 [Target identity:33%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91675.1} I3ZNS6 [Target identity:22%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91680.1}	Show » « Hide Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0006629 [lipid metabolic process]	139	16	No	2
FADS1-006	ENSP00000391229 ENST00000448607	C9J425 Show all » « Hide C9J425 [Target identity:100%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000391229}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)		47	5.4	No	0
FADS1-007	ENSP00000429016 ENST00000491310	I3ZNN6 Show all » « Hide I3ZNN6 [Target identity:33%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91640.1} I3ZNT3 [Target identity:32%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91687.1} I3ZNS3 [Target identity:31%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91677.1} I3ZNS1 [Target identity:26%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91675.1} I3ZNS6 [Target identity:17%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91680.1}	Show » « Hide Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0020037 [heme binding]	175	19.7	No	2
FADS1-009	ENSP00000446270 ENST00000466716	F5H2H3 Show all » « Hide F5H2H3 [Target identity:99%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000446270} F5H0Y2 [Target identity:98%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000439790} F5H1Q7 [Target identity:77%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000438997} I3ZNN6 [Target identity:52%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91640.1} I3ZNT3 [Target identity:51%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91687.1} I3ZNS3 [Target identity:49%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91677.1} C9J425 [Target identity:42%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000391229} I3ZNS1 [Target identity:41%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91675.1} I3ZNS6 [Target identity:27%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91680.1}	Show » « Hide Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)		111	12.7	No	2
FADS1-010	ENSP00000445442 ENST00000473263		Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)		16	1.8	No	0
FADS1-012	ENSP00000441403 ENST00000542506	O60427 Show all » « Hide O60427 [Direct mapping] Fatty acid desaturase 1 F5H852 [Target identity:45%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000442170} F5GYH4 [Target identity:42%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000440652} F5H3P6 [Target identity:40%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000445253} C9JJB3 [Target identity:38%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000416043} F5H8G5 [Target identity:34%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000443587} F5H5X5 [Target identity:31%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000443037} F5H2H3 [Target identity:30%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000446270} F5H0Y2 [Target identity:30%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000439790} F5H1Q7 [Target identity:23%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000438997} I3ZNN6 [Target identity:16%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91640.1} I3ZNS3 [Target identity:15%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91677.1} I3ZNT3 [Target identity:15%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91687.1} C9J425 [Target identity:13%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000391229} I3ZNS1 [Target identity:12%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91675.1} I3ZNL2 [Target identity:11%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91616.1} I3ZNH3 [Target identity:10%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91577.1} I3ZNL9 [Target identity:10%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91623.1} I3ZNS6 [Target identity:8%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91680.1} I3ZNE3 [Target identity:6%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91547.1}	Show » « Hide Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000248 [C-5 sterol desaturase activity] GO:0005506 [iron ion binding] GO:0005739 [mitochondrion] GO:0005789 [endoplasmic reticulum membrane] GO:0006355 [regulation of transcription, DNA-templated] GO:0006629 [lipid metabolic process] GO:0006636 [unsaturated fatty acid biosynthetic process] GO:0007267 [cell-cell signaling] GO:0008654 [phospholipid biosynthetic process] GO:0009267 [cellular response to starvation] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016491 [oxidoreductase activity] GO:0020037 [heme binding] GO:0033559 [unsaturated fatty acid metabolic process] GO:0036109 [alpha-linolenic acid metabolic process] GO:0043231 [intracellular membrane-bounded organelle] GO:0043651 [linoleic acid metabolic process] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0045595 [regulation of cell differentiation] GO:0046456 [icosanoid biosynthetic process] GO:0055114 [oxidation-reduction process]	360	42.5	No	4
FADS1-013	ENSP00000443587 ENST00000539999	F5H8G5 Show all » « Hide F5H8G5 [Target identity:100%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000443587} I3ZNL2 [Target identity:32%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91616.1} I3ZNL9 [Target identity:31%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91623.1} I3ZNH3 [Target identity:29%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91577.1}	Show » « Hide Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)		124	15.3	No	2
FADS1-014	ENSP00000439790 ENST00000544309	F5H0Y2 Show all » « Hide F5H0Y2 [Target identity:100%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000439790} F5H1Q7 [Target identity:78%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000438997} I3ZNN6 [Target identity:53%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91640.1} I3ZNT3 [Target identity:52%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91687.1} I3ZNS3 [Target identity:50%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91677.1} C9J425 [Target identity:43%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000391229} I3ZNS1 [Target identity:42%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91675.1} I3ZNS6 [Target identity:28%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91680.1}	Show » « Hide Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)		109	12.4	No	2
FADS1-016	ENSP00000441871 ENST00000540767	F5GWE3 Show all » « Hide F5GWE3 [Target identity:100%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000441871} F5H852 [Target identity:99%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000442170} F5GYH4 [Target identity:92%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000440652} C9JJB3 [Target identity:84%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000416043} F5H5X5 [Target identity:67%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000443037} F5H0Y2 [Target identity:66%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000439790} F5H2H3 [Target identity:66%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000446270} F5H1Q7 [Target identity:52%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000438997} I3ZNN6 [Target identity:35%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91640.1} I3ZNT3 [Target identity:34%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91687.1} I3ZNS3 [Target identity:33%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91677.1} C9J425 [Target identity:28%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000391229} I3ZNS1 [Target identity:27%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91675.1} I3ZNS6 [Target identity:18%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91680.1}	Show » « Hide Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0006629 [lipid metabolic process]	165	19	No	2
FADS1-017	ENSP00000443037 ENST00000544696	F5H5X5 Show all » « Hide F5H5X5 [Target identity:100%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000443037} F5H2H3 [Target identity:98%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000446270} F5H0Y2 [Target identity:97%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000439790} F5H1Q7 [Target identity:76%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000438997} I3ZNN6 [Target identity:51%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91640.1} I3ZNT3 [Target identity:50%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91687.1} I3ZNS3 [Target identity:49%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91677.1} C9J425 [Target identity:41%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000391229} I3ZNS1 [Target identity:41%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91675.1} I3ZNS6 [Target identity:27%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91680.1}	Show » « Hide Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)		112	12.8	No	2
FADS1-018	ENSP00000440652 ENST00000545405	F5GYH4 Show all » « Hide F5GYH4 [Target identity:100%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000440652} C9JJB3 [Target identity:90%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000416043} F5H5X5 [Target identity:73%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000443037} F5H0Y2 [Target identity:71%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000439790} F5H2H3 [Target identity:71%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000446270} F5H1Q7 [Target identity:56%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000438997} I3ZNN6 [Target identity:37%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91640.1} I3ZNT3 [Target identity:37%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91687.1} I3ZNS3 [Target identity:35%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91677.1} C9J425 [Target identity:30%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000391229} I3ZNS1 [Target identity:30%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91675.1} I3ZNS6 [Target identity:20%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91680.1}	Show » « Hide Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0006629 [lipid metabolic process]	153	17.7	No	2
FADS1-019	ENSP00000442170 ENST00000545245	F5H852 Show all » « Hide F5H852 [Target identity:100%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000442170} F5GYH4 [Target identity:93%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000440652} C9JJB3 [Target identity:84%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000416043} F5H5X5 [Target identity:68%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000443037} F5H2H3 [Target identity:67%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000446270} F5H0Y2 [Target identity:66%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000439790} F5H1Q7 [Target identity:52%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000438997} I3ZNN6 [Target identity:35%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91640.1} I3ZNT3 [Target identity:34%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91687.1} I3ZNS3 [Target identity:33%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91677.1} C9J425 [Target identity:28%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000391229} I3ZNS1 [Target identity:28%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91675.1} I3ZNS6 [Target identity:18%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91680.1}	Show » « Hide Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0006629 [lipid metabolic process]	164	18.9	No	2
FADS1-020	ENSP00000438997 ENST00000539419	F5H1Q7 Show all » « Hide F5H1Q7 [Target identity:100%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000438997} C9J425 [Target identity:54%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000391229}	Show » « Hide Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)		86	9.8	No	1
FADS1-022	ENSP00000439097 ENST00000536991	F5H3U5 Show all » « Hide F5H3U5 [Target identity:100%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000439097} F5H3P6 [Target identity:76%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|Ensembl:ENSP00000445253} I3ZNL2 [Target identity:20%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91616.1} I3ZNL9 [Target identity:20%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91623.1} I3ZNH3 [Target identity:19%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91577.1} I3ZNE3 [Target identity:11%; Query identity:100%] Fatty acid desaturase 1 {ECO:0000313\|EMBL:AFL91547.1}	Show » « Hide Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0006629 [lipid metabolic process]	192	22.7	Yes	3

The Human Protein Atlas project is funded by the Knut & Alice Wallenberg foundation.