NAPRT

GENE INFORMATION

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Gene name

NAPRT (HGNC Symbol)

Synonyms

NAPRT1, PP3856

Description

Nicotinate phosphoribosyltransferase (HGNC Symbol)

Entrez gene summary

Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).[supplied by OMIM, Mar 2008]

Chromosome

8

Cytoband

q24.3

Chromosome location (bp)

143574785 - 143578649

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000147813 (version 78.38)

Entrez gene

93100

UniProt

Q6XQN6 (UniProt - Evidence at protein level)

neXtProt

NX_Q6XQN6

Antibodypedia

NAPRT antibodies
 

PROTEIN VIEW

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NAPRT-002
 
NAPRT-003
 
NAPRT-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NAPRT-002 ENSP00000401508
ENST00000449291
Q6XQN6
Show all »
Show » Show » 538 57.6 No 0
NAPRT-003 ENSP00000390949
ENST00000426292
Q6XQN6
Show all »
Show » Show » 525 56.1 No 0
NAPRT-004 ENSP00000405670
ENST00000435154
C9J8U2
Show all »
Show » Show » 490 52.2 No 0