DPYS

GENE INFORMATION

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Gene name

DPYS (HGNC Symbol)

Synonyms

DHPase

Description

Dihydropyrimidinase (HGNC Symbol)

Entrez gene summary

Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria. [provided by RefSeq, Jul 2008]

Chromosome

8

Cytoband

q22.3

Chromosome location (bp)

104330324 - 104467053

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000147647 (version 78.38)

Entrez gene

1807

UniProt

Q14117 (UniProt - Evidence at protein level)

neXtProt

NX_Q14117

Antibodypedia

DPYS antibodies
 

PROTEIN VIEW

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DPYS-001
 
DPYS-005
 
DPYS-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DPYS-001 ENSP00000276651
ENST00000351513
Q14117
Show all »
Show » Show » 519 56.6 No 0
DPYS-005 ENSP00000430246
ENST00000521573
E5RG28
Show all »
Show » Show » 150 16.2 No 0
DPYS-007 ENSP00000436654
ENST00000533874
Show » Show » 54 6.4 No 0