TERF1

GENE INFORMATION

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Gene name

TERF1 (HGNC Symbol)

Synonyms

PIN2, TRBF1, TRF, TRF1

Description

Telomeric repeat binding factor (NIMA-interacting) 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products. [provided by RefSeq, Jul 2008]

Chromosome

8

Cytoband

q21.11

Chromosome location (bp)

73008864 - 73048122

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000147601 (version 78.38)

Entrez gene

7013

UniProt

P54274 (UniProt - Evidence at protein level)

neXtProt

NX_P54274

Antibodypedia

TERF1 antibodies
 

PROTEIN VIEW

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TERF1-001
 
TERF1-002
 
TERF1-005
 
TERF1-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TERF1-001 ENSP00000276603
ENST00000276603
P54274
Show all »
Show » Show » 439 50.2 No 0
TERF1-002 ENSP00000276602
ENST00000276602
P54274
Show all »
Show » Show » 419 48.2 No 0
TERF1-005 ENSP00000428838
ENST00000518874
E5RFJ5
Show all »
Show » Show » 168 19 No 0
TERF1-006 ENSP00000430121
ENST00000517390
E7EWM7
Show all »
Show » Show » 186 21.4 No 0