RGS20

GENE INFORMATION

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Gene name

RGS20 (HGNC Symbol)

Synonyms

RGSZ1, ZGAP1

Description

Regulator of G-protein signaling 20 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Chromosome

8

Cytoband

q11.23

Chromosome location (bp)

53851808 - 53959303

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000147509 (version 78.38)

Entrez gene

8601

UniProt

O76081 (UniProt - Evidence at protein level)

neXtProt

NX_O76081

Antibodypedia

RGS20 antibodies
 

PROTEIN VIEW

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RGS20-001
 
RGS20-003
 
RGS20-006
 
RGS20-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RGS20-001 ENSP00000297313
ENST00000297313
O76081
Show all »
Show » Show » 388 43.7 No 0
RGS20-003 ENSP00000276500
ENST00000276500
O76081
Show all »
Show » Show » 241 27.1 No 0
RGS20-006 ENSP00000344630
ENST00000344277
O76081
Show all »
Show » Show » 273 31.5 No 0
RGS20-007 ENSP00000430627
ENST00000522225
B3KSW4
Show all »
Show » Show » 122 14.4 No 0