IL2RG

GENE INFORMATION

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Gene name

IL2RG (HGNC Symbol)

Synonyms

CD132, CIDX, IMD4, SCIDX1

Description

Interleukin 2 receptor, gamma (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder. [provided by RefSeq, Mar 2010]

Chromosome

X

Cytoband

q13.1

Chromosome location (bp)

71107404 - 71112108

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000147168 (version 78.38)

Entrez gene

3561

UniProt

P31785 (UniProt - Evidence at protein level)

neXtProt

NX_P31785

Antibodypedia

IL2RG antibodies
 

PROTEIN VIEW

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IL2RG-001
 
IL2RG-002
 
IL2RG-003
 
IL2RG-004
 
IL2RG-005
 
IL2RG-201
 
IL2RG-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IL2RG-001 ENSP00000423966
ENST00000487883
D6RBW5
Show all »
Show » Show » 176 20.8 No 0
IL2RG-002 ENSP00000423601
ENST00000473378
D6R964
Show all »
Show » Show » 99 11.2 No 0
IL2RG-003 ENSP00000421262
ENST00000482750
Show » Show » 65 7.6 No 0
IL2RG-004 ENSP00000363318
ENST00000374202
P31785
Show all »
Show » Show » 369 42.3 Yes 1
IL2RG-005 ENSP00000425233
ENST00000464642
D6RDW9
Show all »
Show » Show » 220 26.1 No 0
IL2RG-201 ENSP00000363303
ENST00000374188
Q5FC10
Show all »
Show » 98 10.8 No 0
IL2RG-202 ENSP00000388967
ENST00000456850
P31785
Show all »
Show » Show » 179 20.1 No 1