NLGN4X

GENE INFORMATION

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Gene name

NLGN4X (HGNC Symbol)

Synonyms

HLNX, KIAA1260, NLGN, NLGN4

Description

Neuroligin 4, X-linked (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the type-B carboxylesterase/lipase protein family. The encoded protein belongs to a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs large homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Chromosome

X

Cytoband

Chromosome location (bp)

5840637 - 6228863

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000146938 (version 78.38)

Entrez gene

57502

UniProt

Q8N0W4 (UniProt - Evidence at protein level)

neXtProt

NX_Q8N0W4

Antibodypedia

NLGN4X antibodies
 

PROTEIN VIEW

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NLGN4X-001
 
NLGN4X-003
 
NLGN4X-004
 
NLGN4X-201
 
NLGN4X-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NLGN4X-001 ENSP00000275857
ENST00000275857
Q8N0W4
Show all »
Show » Show » 816 91.9 Yes 1
NLGN4X-003 ENSP00000370482
ENST00000381092
Q8N0W4
Show all »
Show » Show » 816 91.9 Yes 1
NLGN4X-004 ENSP00000370485
ENST00000381095
Q8N0W4
Show all »
Show » Show » 816 91.9 Yes 1
NLGN4X-201 ENSP00000370483
ENST00000381093
Q8N0W4
Show all »
Show » Show » 816 91.9 Yes 1
NLGN4X-202 ENSP00000439203
ENST00000538097
B3KMT6
Show all »
Show » Show » 817 91.9 Yes 1