SSC4D

GENERAL INFORMATION

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Gene name

SSC4D

Gene description

Scavenger receptor cysteine rich family, 4 domains

Protein class

Predicted secreted proteins

Predicted localization

Secreted

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (kidney, thyroid gland)
GTEx:Mixed

Protein evidence

Evidence at protein level

Protein localization

Airways epithelium, hepatocytes, renal tubules, Leydig cells, seminal vesicle, adrenal gland, neurons in cerebral cortex and parts of the gastrointestainal tract showed moderate cytoplasmic positivity. Remaining normal tissues were weakly stained or negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 1 antibody.
HPA062611
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (kidney, thyroid gland)

Organ

Expression

GTEx dataset
RNA tissue category:  Mixed

Organ

Expression



GENE INFORMATION

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Gene name

SSC4D (HGNC Symbol)

Synonyms

S4D-SRCRB, SRCRB-S4D, SRCRB4D

Description

Scavenger receptor cysteine rich family, 4 domains (HGNC Symbol)

Entrez gene summary

The scavenger receptor cysteine-rich (SRCR) superfamily is an ancient and highly conserved group of cell surface and/or secreted proteins, some of which are involved in the development of the immune system and the regulation of both innate and adaptive immune responses. Group B SRCR domains usually contain 8 regularly spaced cysteines that give rise to a well-defined intradomain disulfide-bond pattern.[supplied by OMIM, Apr 2004]

Chromosome

7

Cytoband

q11.23

Chromosome location (bp)

76389334 - 76409695

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000146700 (version 78.38)

Entrez gene

136853

UniProt

Q8WTU2 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8WTU2

Antibodypedia

SSC4D antibodies


PROTEIN BROWSER

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ENST00000275560
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SSC4D-001 ENSP00000275560
ENST00000275560
Q8WTU2
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