PURB

GENE INFORMATION

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Gene name

PURB (HGNC Symbol)

Synonyms

PURBETA

Description

Purine-rich element binding protein B (HGNC Symbol)

Entrez gene summary

This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. [provided by RefSeq, Jul 2008]

Chromosome

7

Cytoband

p13

Chromosome location (bp)

44876293 - 44885361

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000146676 (version 78.38)

Entrez gene

5814

UniProt

Q96QR8 (UniProt - Evidence at protein level)

neXtProt

NX_Q96QR8

Antibodypedia

PURB antibodies
 

PROTEIN VIEW

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PURB-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PURB-001 ENSP00000379051
ENST00000395699
Q96QR8
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