RSPO3

GENE INFORMATION

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Gene name

RSPO3 (HGNC Symbol)

Synonyms

FLJ14440, THSD2

Description

R-spondin 3 (HGNC Symbol)

Entrez gene summary

This gene belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of this gene with bone mineral density and risk of fracture. This gene may be involved in tumor development. [provided by RefSeq, Jul 2013]

Chromosome

6

Cytoband

q22.33

Chromosome location (bp)

127118604 - 127197765

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000146374 (version 78.38)

Entrez gene

84870

UniProt

Q9BXY4 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BXY4

Antibodypedia

RSPO3 antibodies
 

PROTEIN VIEW

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RSPO3-002
 
RSPO3-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RSPO3-002 ENSP00000357300
ENST00000368317
Q9BXY4
Show all »
Show » Show » 292 33.2 Yes 0
RSPO3-003 ENSP00000349131
ENST00000356698
Q9BXY4
Show all »
Show » Show » 272 30.9 Yes 0