DDX46

GENE INFORMATION

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Gene name

DDX46 (HGNC Symbol)

Synonyms

FLJ25329, KIAA0801, Prp5, PRPF5

Description

DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA splicing. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2014]

Chromosome

5

Cytoband

q31.1

Chromosome location (bp)

134758779 - 134855133

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000145833 (version 78.38)

Entrez gene

9879

UniProt

Q7L014 (UniProt - Evidence at protein level)

neXtProt

NX_Q7L014

Antibodypedia

DDX46 antibodies
 

PROTEIN VIEW

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DDX46-001
 
DDX46-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DDX46-001 ENSP00000416534
ENST00000452510
Q7L014
Show all »
Show » Show » 1032 117.5 No 0
DDX46-002 ENSP00000346236
ENST00000354283
Q7L014
Show all »
Show » Show » 1031 117.4 No 0