EIF2B5

GENE INFORMATION

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Gene name

EIF2B5 (HGNC Symbol)

Synonyms

EIF-2B, EIF2Bepsilon

Description

Eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa (HGNC Symbol)

Entrez gene summary

This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter. [provided by RefSeq, Nov 2009]

Chromosome

3

Cytoband

q27.1

Chromosome location (bp)

184135038 - 184684758

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000145191 (version 78.38)

Entrez gene

8893

UniProt

Q13144 (UniProt - Evidence at protein level)

neXtProt

NX_Q13144

Antibodypedia

EIF2B5 antibodies
 

PROTEIN VIEW

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EIF2B5-001
 
EIF2B5-003
 
EIF2B5-017
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EIF2B5-001 ENSP00000273783
ENST00000273783
Q13144
Show all »
Show » Show » 721 80.4 No 0
EIF2B5-003 ENSP00000414775
ENST00000432569
C9JRD9
Show all »
Show » 107 11.2 No 0
EIF2B5-017 ENSP00000409142
ENST00000444495
E9PC74
Show all »
Show » Show » 705 78.3 No 0