DLX1

GENE INFORMATION

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Gene name

DLX1

Synonyms

Description

Distal-less homeobox 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-{beta} superfamily members. The encoded protein may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain. This gene is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 2. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Chromosome

2

Cytoband

q31.1

Chromosome location (bp)

172084740 - 172089677

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000144355 (version 78.38)

Entrez gene

1745

UniProt

P56177 (UniProt - Evidence at transcript level)

neXtProt

NX_P56177

Antibodypedia

DLX1 antibodies
 

PROTEIN VIEW

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DLX1-001
 
DLX1-002
 
DLX1-004
 
DLX1-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DLX1-001 ENSP00000354478
ENST00000361725
P56177
Show all »
Show » Show » 255 27.3 No 0
DLX1-002 ENSP00000341786
ENST00000341900
P56177
Show all »
Show » Show » 129 13.5 No 0
DLX1-004 ENSP00000448827
ENST00000469444
F8VXJ2
Show all »
Show » Show » 187 20.5 No 0
DLX1-006 ENSP00000354865
ENST00000361609
J3KP55
Show all »
Show » Show » 171 18.5 No 0