AFF3

GENE INFORMATION

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Gene name

AFF3 (HGNC Symbol)

Synonyms

LAF4, MLLT2-like

Description

AF4/FMR2 family, member 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

2

Cytoband

q11.2

Chromosome location (bp)

99545419 - 100142739

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000144218 (version 78.38)

Entrez gene

3899

UniProt

P51826 (UniProt - Evidence at protein level)

neXtProt

NX_P51826

Antibodypedia

AFF3 antibodies
 

PROTEIN VIEW

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 « 
 
AFF3-001
 
AFF3-002
 
AFF3-003
 
AFF3-005
 
AFF3-006
 
AFF3-007
 
AFF3-008
 
AFF3-009
 
AFF3-010
 
AFF3-014
 
AFF3-015
 
AFF3-201
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AFF3-001 ENSP00000387207
ENST00000409236
P51826
Show all »
Show » Show » 1226 133.5 No 0
AFF3-002 ENSP00000386834
ENST00000409579
P51826
Show all »
Show » Show » 1251 136.4 No 0
AFF3-003 ENSP00000396582
ENST00000423966
C9JC67
Show all »
Show » 155 17.5 No 0
AFF3-005 ENSP00000395068
ENST00000416492
C9JMS1
Show all »
Show » 99 11.6 No 0
AFF3-006 ENSP00000411383
ENST00000424600
C9J847
Show all »
Show » 114 13.3 No 0
AFF3-007 ENSP00000399795
ENST00000441400
C9JZ66
Show all »
Show » 129 14.8 No 0
AFF3-008 ENSP00000393732
ENST00000440445
C9JUC4
Show all »
Show » 155 17.5 No 0
AFF3-009 ENSP00000407448
ENST00000415384
C9JUY1
Show all »
Show » 183 19.9 No 0
AFF3-010 ENSP00000416131
ENST00000427118
Show » 17 2 No 0
AFF3-014 ENSP00000406484
ENST00000432037
C9J622
Show all »
Show » 161 18.2 No 0
AFF3-015 ENSP00000416685
ENST00000445815
H7C4C2
Show all »
Show » 185 20.7 No 0
AFF3-201 ENSP00000317421
ENST00000317233
P51826
Show all »
Show » Show » 1226 133.5 No 0