PRUNE

GENE INFORMATION

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Gene name

PRUNE (HGNC Symbol)

Synonyms

DRES-17, HTCD37

Description

Prune exopolyphosphatase (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the DHH protein superfamily of phosphoesterases. This protein has been found to function as both a nucleotide phosphodiesterase and an exopolyphosphatase. This protein is believed to stimulate cancer progression and metastases through the induction of cell motility. A pseuodgene has been identified on chromosome 13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Chromosome

1

Cytoband

q21.3

Chromosome location (bp)

151008420 - 151035713

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000143363 (version 78.38)

Entrez gene

58497

UniProt

Q86TP1 (UniProt - Evidence at protein level)

neXtProt

NX_Q86TP1

Antibodypedia

PRUNE antibodies
 

PROTEIN VIEW

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PRUNE-001
 
PRUNE-002
 
PRUNE-003
 
PRUNE-004
 
PRUNE-005
 
PRUNE-009
 
PRUNE-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PRUNE-001 ENSP00000271620
ENST00000271620
Q86TP1
Show all »
Show » Show » 453 50.2 No 0
PRUNE-002 ENSP00000357933
ENST00000368937
Q86TP1
Show all »
Show » Show » 218 24.1 No 0
PRUNE-003 ENSP00000357932
ENST00000368936
Q86TP1
Show all »
Show » Show » 271 30.1 No 0
PRUNE-004 ENSP00000357930
ENST00000368934
Q86TP1
Show all »
Show » Show » 218 24.1 No 0
PRUNE-005 ENSP00000357931
ENST00000368935
Q86TP1
Show all »
Show » Show » 168 18.5 No 0
PRUNE-009 ENSP00000392632
ENST00000431193
Q5SZG1
Show all »
Show » Show » 178 19.9 No 0
PRUNE-010 ENSP00000387696
ENST00000450884
Q5SZF2
Show all »
Show » Show » 140 16 No 0