TBX19

GENE INFORMATION

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Gene name

TBX19 (HGNC Symbol)

Synonyms

dj747L4.1, TPIT

Description

T-box 19 (HGNC Symbol)

Entrez gene summary

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

q24.2

Chromosome location (bp)

168281040 - 168314426

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000143178 (version 78.38)

Entrez gene

9095

UniProt

O60806 (UniProt - Evidence at protein level)

neXtProt

NX_O60806

Antibodypedia

TBX19 antibodies
 

PROTEIN VIEW

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TBX19-001
 
TBX19-003
 
TBX19-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TBX19-001 ENSP00000356795
ENST00000367821
O60806
Show all »
Show » Show » 448 48.2 No 0
TBX19-003 ENSP00000390731
ENST00000441464
Show » Show » 281 29.8 No 0
TBX19-004 ENSP00000397540
ENST00000431969
B3KRD9
Show all »
Show » Show » 318 33.8 No 0