CYP4B1

GENE INFORMATION

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Gene name

CYP4B1

Synonyms

Description

Cytochrome P450, family 4, subfamily B, polypeptide 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined. Two transcript variants encoding slightly different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

p33

Chromosome location (bp)

46757838 - 46819413

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000142973 (version 78.38)

Entrez gene

1580

UniProt

P13584 (UniProt - Evidence at protein level)

neXtProt

NX_P13584

Antibodypedia

CYP4B1 antibodies
 

PROTEIN VIEW

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CYP4B1-001
 
CYP4B1-002
 
CYP4B1-003
 
CYP4B1-005
 
CYP4B1-010
 
CYP4B1-011
 
CYP4B1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CYP4B1-001 ENSP00000271153
ENST00000271153
P13584
Show all »
Show » Show » 511 59 No 1
CYP4B1-002 ENSP00000360991
ENST00000371923
P13584
Show all »
Show » Show » 512 59.1 No 1
CYP4B1-003 ENSP00000360987
ENST00000371919
Q8IZB0
Show all »
Show » Show » 497 57.2 No 1
CYP4B1-005 ENSP00000437670
ENST00000468637
F5H6F1
Show all »
Show » Show » 238 28 No 0
CYP4B1-010 ENSP00000438995
ENST00000526297
F5H1Q8
Show all »
Show » Show » 70 8.1 No 0
CYP4B1-011 ENSP00000400413
ENST00000452782
E7EME6
Show all »
Show » Show » 349 40.4 No 0
CYP4B1-201 ENSP00000484629
ENST00000614163
Q8WWV1
Show all »
Show » Show » 295 34.2 No 1