TM4SF5

GENE INFORMATION

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Gene name

TM4SF5

Synonyms

Description

Transmembrane 4 L six family member 5 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is highly similar in sequence and structure to transmembrane 4 superfamily member 1. It may play a role in cell proliferation, and overexpression of this protein may be associated with the uncontrolled growth of tumour cells. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

p13.2

Chromosome location (bp)

4771884 - 4783213

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000142484 (version 78.38)

Entrez gene

9032

UniProt

O14894 (UniProt - Evidence at transcript level)

neXtProt

NX_O14894

Antibodypedia

TM4SF5 antibodies
 

PROTEIN VIEW

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TM4SF5-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TM4SF5-001 ENSP00000270560
ENST00000270560
O14894
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